Hernandez spent three years attending three or four casting calls a week, until he signed a contract to do a commercial and then a small role in the film Propiedad Ajena in 2007. The following year, she had her first supporting role in the film Espiral (2008) and then a 40-second role in the film Sin Nombre, directed by Cary Fukunaga. He then appeared in supporting roles in the films Vaho (2010), Somos Lo Que Hay(2010) and El Infierno (2010).
During the filming of Sin Nombre, Hernández met filmmaker Gerardo Naranjo, who years later offered her the leading role in Miss Bala,45 which was written by Naranjo and Mauricio Katz, the film is about a beauty pageant contestant, played by Stephanie Sigman.
In 2024 he won the Ariel Award for Best Actor for his role in Kokoloko.